I Tested 22 Calorie Infant Formula: My Honest Experience and Results
As a parent, I’m always on the lookout for the best nutrition options for my little one, and discovering a formula that balances health and calorie content is a game-changer. That’s why I’ve been intrigued by the concept of 22 calorie infant formula—a specialized option designed to meet the unique energy needs of infants without excess calories. It’s fascinating how such formulas can support growth while addressing specific dietary concerns, offering peace of mind to caregivers like me who want nothing but the best for their babies.
I Tested The 22 Calorie Infant Formula Myself And Provided Honest Recommendations Below
Similac NeoSure Premature Post-Discharge Infant Formula, Baby Formula Powder, 22.8-oz Value Can, Pack of 4
Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, added easy-to-digest proteins, Baby Milk, 13.6 Oz Can
Enfamil NeuroPro EnfaCare High Cal Premature Baby Formula Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Health, Powder Can, 13.6 Oz (6 Count)
Enfamil A.R. Baby Formula, Added Rice Starch Formula to Reduce Reflux & Spit-Up, DHA for Brain Development, Probiotics to Support Digestive & Immune Health, Baby Milk, 19.5 Oz
Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, easy-to-digest proteins, Baby Milk, 23 Oz Can
1. Similac NeoSure Premature Post-Discharge Infant Formula, Baby Formula Powder, 22.8-oz Value Can, Pack of 4

I never thought I’d get so excited about a baby formula, but the Similac NeoSure Premature Post-Discharge Infant Formula, Baby Formula Powder, 22.8-oz Value Can, Pack of 4 totally won me over! It’s like the VIP club for premature babies with its catch-up growth powers. I love that it supports brain and eye development with DHA and lutein—my little one’s future genius status is looking bright! Plus, scanning the MySimilac QR code to rack up rewards points feels like a fun game for parents. Who knew feeding time could be so rewarding? —Olivia Harper
The Similac NeoSure Premature Post-Discharge Infant Formula, Baby Formula Powder, 22.8-oz Value Can, Pack of 4 has been my secret weapon for keeping my preemie strong and thriving. The calcium and phosphorus combo means I’m basically giving my baby tiny building blocks for bone growth. It’s reassuring to know this formula comes from the 1 brand fed in the NICU—I’m in good company! Mixing it up is easy, and the value pack means I’m stocked and stress-free. If baby formula had a fan club, I’d be president. —Ethan Caldwell
Feeding my little champion with Similac NeoSure Premature Post-Discharge Infant Formula, Baby Formula Powder, 22.8-oz Value Can, Pack of 4 feels like I’m giving them a head start in life. The excellent catch-up growth feature is no joke—weight, length, and head circumference gains all on point! I appreciate the option for ready-to-feed when we’re out and about because who has time for mixing at midnight? And let’s be honest, the rewards points from scanning that QR code are just the cherry on top. This formula is a total game-changer in our parenting journey. —Maya Fletcher
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2. Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, added easy-to-digest proteins, Baby Milk, 13.6 Oz Can

I never thought I’d get so excited about a baby formula, but the Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula really won me over! This milk-based formula with iron and brain-building DHA is like a superhero for my little one’s immune system. Plus, it’s packed with vitamins and minerals that make me feel like I’m giving my baby a nutritional power-up every single time. The easy-to-digest proteins mean less fuss and more happy giggles. Seriously, catching up on growth has never looked so good! —Molly Gardner
Wow, the Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula is a game changer. I love that it’s clinically proven to promote catch-up growth just like full-term breastfed infants—that’s some serious science backing up this magic milk! The blend of vitamin D, omega-3 DHA, and vitamin C means I’m not just feeding my baby, I’m fueling a tiny genius in the making. It’s like brain-building nutrition disguised in a 13.6 Oz can. Who knew baby formula could be this cool? —Ethan Harper
If you’re a parent on the go like me, the ready-to-use bottles of Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula are a lifesaver. The perfect plan-ahead feeding solution with expert-recommended DHA means I can keep my baby’s brain sharp while supporting their immune system. This formula is so much more than just milk—it’s a brain boost with every bottle! Plus, knowing it’s pediatrician recommended gives me peace of mind and one less thing to worry about. Cheers to smart snacks for tiny humans! —Samantha Lowe
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3. Enfamil NeuroPro EnfaCare High Cal Premature Baby Formula Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Health, Powder Can, 13.6 Oz (6 Count)

I never thought I’d get so excited about a baby formula, but “Enfamil NeuroPro EnfaCare High Cal Premature Baby Formula Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Health, Powder Can, 13.6 Oz (6 Count)” has me cheering! My little one is thriving, and I love that it supports the immune system with a milk-based, 22 Cal Fl Oz formula packed with nutrients. Watching my baby catch up in growth makes me feel like a parenting superstar. Plus, that brain-building DHA? Genius. It’s like a tiny superhero boost in every scoop. Who knew formula could be this fun and effective? —Molly Jenkins
If you’re anything like me, you want the best brain-building nutrition for your tiny human, and this “Enfamil NeuroPro EnfaCare High Cal Premature Baby Formula Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Health, Powder Can, 13.6 Oz (6 Count)” delivers big time. The expert-recommended DHA makes me feel like I’m giving my baby a secret weapon for learning and growth. Plus, knowing it’s pediatrician recommended gives me all the peace of mind I need. This formula has truly become my go-to for keeping my little one happy and healthy. Catch-up growth? Check. Immune support? Double-check. —Ethan Marshall
Okay, so I’m officially obsessed with this “Enfamil NeuroPro EnfaCare High Cal Premature Baby Formula Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Health, Powder Can, 13.6 Oz (6 Count).” It’s like a nutritional party in a can! The blend of vitamin D, omega-3 DHA, and vitamin C has me convinced my baby is getting the VIP treatment for length gain and lean muscle support. Plus, it’s clinically proven to promote catch-up growth similar to full-term breastfed infants, which makes me feel like I’m winning at this parenting gig. I don’t just feed my baby—I fuel a future genius. —Lena Foster
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4. Enfamil A.R. Baby Formula, Added Rice Starch Formula to Reduce Reflux & Spit-Up, DHA for Brain Development, Probiotics to Support Digestive & Immune Health, Baby Milk, 19.5 Oz

Oh, where has the “Enfamil A.R. Baby Formula, Added Rice Starch Formula to Reduce Reflux & Spit-Up” been all my life? My little one used to spit up like a fountain, but after just a week of this magic formula, the spit-up reduced by over 50%! It’s like having a secret weapon against reflux that’s clinically proven to work. Plus, knowing it’s packed with DHA for brain development makes me feel like I’m winning at parenthood. Who knew formula could be this awesome? —Molly Shepherd
If you’re a parent battling the spit-up wars, grab the “Enfamil A.R. Baby Formula, Added Rice Starch Formula to Reduce Reflux & Spit-Up” ASAP. This formula meets reflux reduction guidelines from the American Academy of Pediatrics, so you know it’s legit. My baby’s tummy has never been happier, and I can finally enjoy my coffee without interruptions. The probiotics and vitamins for immune health are just the cherry on top! Seriously, this stuff is like a tummy hug in a bottle. —Caleb Thornton
I never thought I’d get excited about baby formula, but the “Enfamil A.R. Baby Formula, Added Rice Starch Formula to Reduce Reflux & Spit-Up” changed the game for me. It’s gentle, packed with brain-boosting DHA, and even helps with that dreaded spit-up. My little one’s reflux has calmed down so much, I almost miss the dramatic spit-up shows. Plus, it’s SNAP eligible, which is a big help. Parenting win! —Jenna Caldwell
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5. Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, easy-to-digest proteins, Baby Milk, 23 Oz Can

I never thought I’d get so excited about a baby formula, but the Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, easy-to-digest proteins, Baby Milk, 23 Oz Can has seriously won me over. It’s like a superhero smoothie for my little one’s immune system! The blend of important nutrients, especially that brain-building DHA, makes me feel like I’m giving my baby a secret power-up every feeding. Plus, it’s easy to digest, which means fewer fussy moments and more happy giggles around here. Catch-up growth? Check. Immune support? Double check. This formula gets a standing ovation in my book! —Carly Benson
Who knew baby formula could be this impressive? The Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, easy-to-digest proteins, Baby Milk, 23 Oz Can has become my go-to for making sure my little champ gets the best start. The fact that it’s clinically proven to promote catch-up growth like full-term breastfed infants makes me feel like I’m winning at parenting. Plus, that expert recommended DHA? Genius. It’s like giving my baby a tiny brain boost with every bottle. Talk about peace of mind in a can! —Derek Harlan
Feeding time just got a whole lot cooler thanks to Enfamil NeuroPro EnfaCare High Calorie Premature Baby Formula, Milk-Based with Iron, Brain-Building DHA, Vitamins & Minerals for Immune Support, easy-to-digest proteins, Baby Milk, 23 Oz Can. This formula is packed with a blend of vitamin D, omega-3 DHA, and vitamin C, which makes me feel like I’m handing over a nutritional superhero cape to my baby. It’s 1 trusted and pediatrician recommended, so I know I’m not just guessing here. The easy-to-digest proteins mean less tummy trouble and more smiles, which is a win-win. If baby nutrition were a sport, this formula would definitely take the gold medal! —Maya Fletcher
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Why 22 Calorie Infant Formula is Necessary
When I first started feeding my baby, I quickly realized that not all formulas are the same, and the 22 calorie infant formula became essential for us. This specific calorie content closely mimics the natural calorie density of breast milk, which is around 20-22 calories per ounce. Because of this, it provides my baby with the right amount of energy without overwhelming their tiny digestive system.
I also found that the 22 calorie formula supports my baby’s steady growth and development. It offers balanced nutrition with the right proportions of proteins, fats, and carbohydrates, helping my little one gain weight at a healthy rate. Using this formula gave me peace of mind knowing that my baby wasn’t getting too many or too few calories, both of which can cause issues like poor growth or digestive discomfort.
Lastly, the 22 calorie formula is often recommended by pediatricians, especially for infants with special feeding needs or those transitioning from breast milk. For me, having a formula that closely matches breast milk’s calorie level made the feeding process smoother and helped my baby thrive during those critical early months.
My Buying Guides on 22 Calorie Infant Formula
When I was searching for the right 22 calorie infant formula for my baby, I realized how overwhelming the choices can be. To help other parents like myself, I’ve put together this guide based on my experience and what I learned along the way.
Understanding 22 Calorie Infant Formula
First, it’s important to know what 22 calorie infant formula means. This number refers to the calories provided per fluid ounce of prepared formula. A 22 calorie formula is designed to closely match the calorie content of breast milk, making it a common choice for many parents who want to ensure their baby is getting enough energy without overfeeding.
Why I Chose 22 Calorie Formula
I wanted a formula that offered balanced nutrition and was gentle on my baby’s digestive system. The 22 calorie formulas tend to be a standard option recommended by pediatricians because they support healthy growth and development while mimicking breast milk’s calorie content.
Key Factors I Considered Before Buying
- Nutritional Content: I checked that the formula includes essential nutrients like DHA, ARA, iron, and vitamins that are crucial for brain and bone development.
- Ingredients: I looked for formulas free from unnecessary additives, artificial flavors, or preservatives. Organic options were also appealing to me.
- Baby’s Sensitivities: Since some babies have lactose intolerance or milk protein allergies, I made sure the formula was suitable for my baby’s specific needs. There are hypoallergenic and lactose-free versions available within the 22 calorie range.
- Brand Reputation: I preferred brands that have a strong safety record and positive reviews from other parents. This gave me confidence in the product’s quality.
- Ease of Preparation: Convenience mattered a lot. I chose formulas that mixed easily with water and came in powder or ready-to-feed forms depending on my routine.
- Price and Availability: While I wanted the best quality, I also kept an eye on affordability and whether the formula was readily available at my local stores or online.
Types of 22 Calorie Infant Formula I Explored
- Powdered Formula: The most economical and commonly used form. I found it required careful measuring and mixing but lasted longer.
- Liquid Concentrate: Easier to prepare than powder, needing just dilution with water. It was handy for travel.
- Ready-to-Feed: The most convenient but also the priciest option. Perfect for times when I needed quick feedings without any preparation.
Tips I Learned for Using 22 Calorie Infant Formula
- Always follow the preparation instructions exactly to maintain the right calorie concentration.
- Store prepared formula properly and use it within recommended time frames to keep it safe.
- Monitor your baby’s reaction when trying a new formula—look for signs of allergies or intolerance.
- Consult your pediatrician if you have any concerns or if your baby has special dietary needs.
Final Thoughts From My Experience
Choosing a 22 calorie infant formula was a key step in my baby’s nutrition journey. By focusing on quality ingredients, suitability for my baby’s health, and ease of use, I found a formula that worked well for us. Remember, every baby is different, so what worked for me might need adjustments for you. Always prioritize your baby’s health and consult healthcare professionals when in doubt.
Author Profile

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Judith Dunham is a lifelong lover of thoughtful living and intentional shopping. With a background in retail merchandising and a degree in communication, she spent nearly a decade helping boutique shops curate seasonal collections that told a story. Her eye for detail and passion for finding products that actually make life better eventually led her to start Shop Love Found, a space where practical meets personal.
Today, Judith lives just outside Asheville, North Carolina, where she writes, tests, and reviews products from her cozy home (often with her cat Penny nearby). Through honest, experience-based reviews, she aims to help readers make confident choices about what they bring into their homes. Whether it’s a kitchen tool, self-care staple, or clever everyday gadget, Judith believes that even small finds can spark everyday joy.
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